High-resolution x-ray 3D imaging of bone micro-structure
Osteoporosis impact on public health is sharply increasing justifying a significant effort to diagnose, reat and understand this disease. Bones have been imaged with x-rays for almost a century and the basic technology for clinical image is well established, but with the recent development of large scale synchrotron light sources and high-end microfiches x-ray generators, imaging of the intricate bone inner structure with a few micron resolution become possible. Laser driven betatron x-ray microscope was built and used to demonstrate the feasibility of high-resolution bone imaging in the Astra-Gemini laser facility (UK). A sample of femur trabecular bone was imaged from multiple angles and a 3D model of the bone was built using tomographic techniques to a resolution below 50 micron. This demonstration renew the interest in the development of compact laser-plasma electron accelerators and its applications. It also opens prospects for its use in clinic diagnostics in the medium term.
Welcome to the website of the X-GoLP team, the experimental team of the Group for Lasers and Plasmas of the Instituto de Plasmas e Fusão Nuclear at Instituto Superior Técnico.
On Monday,27th of November at 2:00 pm, there will be a GoLP VIP Seminar by Hamed Merdji (Laboratoire d’Optique Appliquée Ecole Polytechnique, Palaiseau, France). The event will take place at Anfiteatro Abreu Faro – Complexo I at IST.Title: From classical to the quantum nature of high harmonic generation
Part 1 – Classical HHG : I will first present classical high-harmonic generation in semiconductor as a light up-conversion process occurring in a strong…
APPLAuSE student Joana Alves successfully defended her PhD thesis entitled “Ultrafast mid-infrared unable sources” on September 19, 2023. Her work was supervised by Gonçalo Figueira, Hugo Pires (both at IPFN/IST) and Jens Biegert (ICFO, Spain).
During her PhD, Joana specialised in the study of ultrafast mid-infrared (wavelengths from 3-8 µm) laser technology, in particular nonlinear amplification of ultrashort pulses and their compression.
She evaluated strategies for…