High-resolution x-ray 3D imaging of bone micro-structure
Osteoporosis impact on public health is sharply increasing justifying a significant effort to diagnose, reat and understand this disease. Bones have been imaged with x-rays for almost a century and the basic technology for clinical image is well established, but with the recent development of large scale synchrotron light sources and high-end microfiches x-ray generators, imaging of the intricate bone inner structure with a few micron resolution become possible. Laser driven betatron x-ray microscope was built and used to demonstrate the feasibility of high-resolution bone imaging in the Astra-Gemini laser facility (UK). A sample of femur trabecular bone was imaged from multiple angles and a 3D model of the bone was built using tomographic techniques to a resolution below 50 micron. This demonstration renew the interest in the development of compact laser-plasma electron accelerators and its applications. It also opens prospects for its use in clinic diagnostics in the medium term.
Welcome to the website of the X-GoLP team, the experimental team of the Group for Lasers and Plasmas of the Instituto de Plasmas e Fusão Nuclear at Instituto Superior Técnico.
The paper “Ultra-broadband near-IR NOPAs based on the nonlinear crystals BiBO and YCOB” by Mario Galletti et al. is featured on the cover of the latest issue of the journal High Power Laser Science and Engineering.
In this work, the GoLP/IPFN researchers from Universidade de Lisboa, in collaboration with colleagues from the Central Laser Facility, STFC, United Kingdom, consider two alternative crystals for both low- and high-energy,…
Thomas Wodzinski defended successfully his PhD thesis on October 14, 2020 and passed with Distinction. He was awarded a fellowship in the APPLAuSE doctoral program on Plasma Science and Engineering in 2015 and joined GoLP for his thesis under the supervision of Prof. Dr. Marta Fajardo (IST) and Dr. Elke Plönjes-Palm (FLASH, DESY).
During his PhD, Thomas performed research at the Laboratory for Intense Lasers…